Drug Standards
Medchemexpress LLC Fexofenadine | 83799-24-0 | >99.8% | 50 MG
Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. It is used in allergic rhinitis and chronic idiopathic urticarial research. Fexofenadine inhibits the expression of IL-6 protein in nasal fibroblasts in a dose-dependent manner and blocks phosphorylated p38 activation in histamine-induced nasal fibroblasts. In animal models, Fexofenadine hydrochloride has been shown to suppress both eosinophilia and systemic anaphylaxis in mice infected with *T. spiralis*.
- Orally active and nonsedative H1 receptor antagonist.
- Useful in allergic rhinitis and chronic idiopathic urticarial research.
- Inhibits IL-6 protein expression in nasal fibroblasts.
- Blocks phosphorylated p38 activation in histamine-induced nasal fibroblasts.
- Suppresses eosinophilia and systemic anaphylaxis in animal models.
Medchemexpress LLC Fexofenadine hydrochloride | 153439-40-8 | 99.9% | 5 MG
Fexofenadine hydrochloride is an orally active and nonsedative H1 receptor antagonist. It can be used in allergic rhinitis and chronic idiopathic urticarial research.
- Orally active
- Nonsedative H1 receptor antagonist
- Can be used in allergic rhinitis research
- Can be used in chronic idiopathic urticarial research
- Inhibits the expression of IL-6 protein in nasal fibroblasts in a dose-dependent manner
- Blocks phosphorylated p38 activation in histamine-induced nasal fibroblasts
- Suppresses eosinophilia and systemic anaphylaxis in T. spiralis infected mice
Medchemexpress LLC Fluticasone | 90566-53-3 | 98.7% | 1 MG
Fluticasone is an inhaled corticosteroid utilized in respiratory research. It functions as a Smo agonist with an IC50 value of 99 nM. This compound is known to activate Hedgehog signaling and encourage the proliferation of primary neuronal stem or precursor cells.
- Inhibits U2OS cell growth with an EC50 value of 99 nM
- Decreases HRV-induced mucin production
- Suppresses rhinovirus-induced airways inflammation in vivo
- Activates Hedgehog signaling
- Promotes proliferation of primary neuronal stem or precursor cells
Sigma Aldrich Fine Chemicals Biosciences Clioquinol British Pharmacopoeia (BP) Reference Standard | 130-26-7 | MFCD00006787 |
Clioquinol British Pharmacopoeia (BP) Reference Standard | Mol Wt: 305.5 | 130-26-7 | MFCD00006787 |
Sigma Aldrich Fine Chemicals Biosciences Meclizine hydrochloride United States Pharmacopeia (USP) Reference Standard | 31884-77-2 | 500MG
Meclizine hydrochloride United States Pharmacopeia (USP) Reference Standard | Mol Wt: 481.89 | 31884-77-2 | 500MG
Sigma Aldrich Fine Chemicals Biosciences Low Molecular Weight Heparin for Boron Analysis United States Pharmacopeia (USP) Reference Standard | 9041-08-1 | 300MG
Low Molecular Weight Heparin for Boron Analysis United States Pharmacopeia (USP) Reference Standard | 9041-08-1 | 300MG
Echelon Biosciences Research Labs PIK-93 5 mg
PIK-93 is the first reported PI4-kinase inhibitor, which is able to inhibit PI4KIII at low-nanomolar range (IC50=19 nM). In addition, this compound is a potent inhibitor of PI3K in vitro (IC50=16 nM). This compound inhibits p110, p110, p110 with IC50s of 0.039, 0.59, 0.12 M respectively. PIK-93 hydrogen bonds to the backbone amide and carbonyl of Val882 and between its sulphonamide and Asp964. PI4KIII is esential for replication of numerous viruses P. falciparum. Inhibition of plasmodial PI4KIII has been proposed as an anti-malaria treatment. This item is non returnable
Cayman Chemical SynthetIc OuabaIn-d3 1mg
An internal standard for the quantification of ouabain by GC- or LC-MS
Apexbio Technology LLC Larotrectinib 1223403-58-4 5mg
Larotrectinib (CAS 1223403-58-4) is a selective orally bioavailable inhibitor of tropomyosin receptor kinases (Trk) which are receptor tyrosine kinases implicated in oncogenic signaling upon neurotrophin activation By binding to Trk proteins larotrectinib disrupts neurotrophin-mediated phosphorylation and downstream signaling leading to growth inhibition and induction of apoptosis in tumor models with Trk gene fusions or overexpression It has gained regulatory approval for use in the study and treatment of solid tumors harboring Trk alterations supporting its application in preclinical and clinical oncology research focused on Trk-driven malignancies
Apexbio Technology LLC Betahistine 2HCl 5579-84-0 1g
Betahistine 2HCl (CAS 5579-84-0) is a small-molecule inhibitor targeting histamine H3 receptors exhibiting an inhibitory concentration (IC50) of 1 9 M By antagonizing H3 receptors betahistine modulates histaminergic neurotransmission which influences the release of various neurotransmitters in the central nervous system This compound is widely utilized in research focused on the physiological roles of histamine signaling particularly in studies of neurological and vestibular disorders as well as in the exploration of H3 receptor pharmacology and modulation
Sigma Aldrich Fine Chemicals Biosciences Fenbendazole Related Compound B United States Pharmacopeia (USP) Reference Standard | 20367-38-8 | 30MG
Fenbendazole Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 225.63 | 20367-38-8 | 30MG
![eMolecules Synthonix - Stock Tributyl[(1E)-2-(trimethylsilyl)ethenyl]stannane 1g 525923828 T2490 58207-97-9 [null] 389.286 C17H38SiSn](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696588.jpg-250.jpg)
eMolecules Synthonix - Stock Tributyl[(1E)-2-(trimethylsilyl)ethenyl]stannane 1g 525923828 T2490 58207-97-9 [null] 389.286 C17H38SiSn
Synthonix - Stock Tributyl[(1E)-2-(trimethylsilyl)ethenyl]stannane 1g 525923828 T2490 58207-97-9 [null] 389.286 C17H38SiSn
Sigma Aldrich Fine Chemicals Biosciences Lidocaine powder100G
Lidocaine is a local anesthetic and an effective antiarrhythmianbspagent. It occurs as SOLUTIONons of crystalline colorless solid for injections that has a short half-life within plasma.
Sigma Aldrich Fine Chemicals Biosciences Betaine United States Pharmacopeia (USP) Reference Standard | 107-43-7 | MFCD00012123 | 1G
Betaine United States Pharmacopeia (USP) Reference Standard | Mol Wt: 117.15 | 107-43-7 | MFCD00012123 | 1G
Sigma Aldrich Fine Chemicals Biosciences Acemetacin European Pharmacopoeia (EP) Reference Standard | 53164-05-9 | MFCD00151473 |
Acemetacin European Pharmacopoeia (EP) Reference Standard | Mol Wt: 415.82 | 53164-05-9 | MFCD00151473 |